CAT #: KMT2A MRD

KMT2A MRD Assay

CONTACT US ⟶
  • Description of Test:

    LabPMM’s KMT2A MRD assay is a highly sensitive digital PCR-based test that uses RNA to detect and quantify most  MLLT3 (AF9), MLLT10 (AF10), ELL, and MLLT4/AFDN (AF6) rearrangements of the KMT2A gene (KMT2Ar), with a sensitivity of 5 x10-5 (0.005%).

    Breakpoints detected:

  • Overview:

    Certain rearrangements of the KMT2A gene are associated with both de novo or therapy-induced acute leukemia and generally confer an adverse prognosis, making the molecular biomarker a valuable tool for measurable residual disease detection, risk stratification, disease monitoring and biomarker discovery.1,2,3

     

Service Details

Legal Notice

References

1. Meyer et al. (2023) Nature. https://doi.org/10.1038/s41375-023-01877-1
2. Zhang et al. (2025) Blood Cancer J. https://doi.org/10.1038/s41408-025-01293-x
3. Young et al. (2023) J Mol Diagn. https://doi.org/10.1016/j.jmoldx.2023.09.006.

Now Available

Our New Document Search Feature
SEARCH ⟶

Need Help Placing an Online Order?

Contact our Customer Service Team
CONTACT CUSTOMER SERVICE ⟶

Now Available

Our New Document Search Feature
SEARCH ⟶

Need Help Placing an Online Order?

Contact our Customer Service Team
CONTACT CUSTOMER SERVICE ⟶