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CAT #: 23100101

BCR/ABL t(9;22) Mix 3d - 6FAM for ABI Fluorescence Detection

Product Use

BCR/ABL t(9;22) Mix 3d – 6FAM for ABI Fluorescence Detection is a Research Use Only master mix that can be used to identify BCR/ABL t(9;22) translocations.

Product Details

  • Description

    BCR/ABL translocations are associated with a variety of hematologic malignancies.  The Philadelphia chromosome (Ph1) is a specific chromosomal abnormality that results from reciprocal t(9;22)(q34;ql1) chromosomal rearrangements fuse coding regions of the BCR gene, located on chromosome 22, with the ABL receptor-independent tyrosine kinase gene on chromosome 9.

    The BCR/ABL t(9;22) Mix 3d master mix targets all p210- and p230-type BCR/ABL transcripts.  PCR products are differentially labeled with 6FAM and can be analyzed using any platform that has the ability to detect these fluorochromes.

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