CAT #: 23100010
BCR/ABL t(9;22) Mix 1a - Unlabeled for Gel Detection
BCR/ABL t(9;22) Mix 1a – Unlabeled for Gel Detection is a Research Use Only master mix that can be used to identify BCR/ABL t(9;22) translocations.
BCR/ABL translocations are associated with a variety of hematologic malignancies. The Philadelphia chromosome (Ph1) is a specific chromosomal abnormality that results from reciprocal t(9;22)(q34;ql1) chromosomal rearrangements fuse coding regions of the BCR gene, located on chromosome 22, with the ABL receptor-independent tyrosine kinase gene on chromosome 9.
The BCR/ABL t(9;22) Mix 1a master mix targets the Abl gene, serving as an internal control. PCR products can be analyzed using standard gel electrophoresis using heteroduplex analysis with ethidium staining.
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This product is for Research Use Only; not for use in diagnostic procedures.
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