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B Cell Gene Rearrangement/Clonality Assays
Identifies clonal rearrangements of the immunoglobulin heavy (IGH) chain gene and determine the somatic mutation status of the variable (V) gene sequence in patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).
Identifies IGH gene rearrangements using 3 master mixes that target the FrameWork 1-3 regions.
Identifies IGH gene rearrangements using 3 master mixes that target the FrameWork 1-3 regions and 2 master mixes that target the DH-JH rearrangements.
Identifies IGK gene rearrangements using 2 master mixes that target the Vk1-7 segments, the Kappa deletion element, and intron segment.
Identifies IGL gene rearrangements using 1 master mix that targets the Vl1-3 segments.